• Microgravity Increases Therapeutic Efficacy of Three-dimensional Cultured Neural Stem Cells in Repairing Spinal Cord Injury
    Microgravity Increases Therapeutic Efficacy of Three-dimensional Cultured Neural Stem Cells in Repairing Spinal Cord Injury

    Researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, indicated the feasibility of combining the RCCS (Rotary Cell Culture System) with collagen scaffold-based 3-D cell culture for producing tissue engineering seed cells in the treatment of spinal cord injury.

    24 Jan 2022
  • Scientists Find New Mechanisms Regulating Endoreduplication in Arabidopsis
    Scientists Find New Mechanisms Regulating Endoreduplication in Arabidopsis

    Researchers led by Prof. LI Yunhai at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS), collaborated with researchers at Henan University and the Institute of Microbiology of CAS, revealed the UBP14/DA3-CDKB1;1-CDKG2/SUD6 regulatory module controls endoreduplication and cell growth in Arabidopsis.

    21 Jan 2022
  • Molecular and Cellular Drivers of Hypothalamic Aging
    Molecular and Cellular Drivers of Hypothalamic Aging

    Recently, a study led by Dr. WU Qingfeng from Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (CAS), revealed five aging hallmarks of the hypothalamus and identified fibroblast-like vascular and leptomeningeal cells (VLMCs) as a critical cell population which might exacerbate aging process through secretory factors.

    21 Jan 2022
  • Uncovered the Mystery of Apical Hook Formation for Seedling Emergence
    Uncovered the Mystery of Apical Hook Formation for Seedling Emergence

    Researchers from Institute of Genetics and Developmental Biology, Chinese Academy of Sciences and the University of Minnesota, United States, uncovered the mechanism of apical hook formation and proposed a molecular framework for auxin-mediated inhibition of cell expansion.

    20 Jan 2022
  • Advances in Biomaterial-Based Spinal Cord Injury Repair Exhibit Great Potential in Clinic
    Advances in Biomaterial-Based Spinal Cord Injury Repair Exhibit Great Potential in Clinic

    Prof. DAI Jianwu from Institute of Genetics and Developmental Biology, the Chinese Academy of Sciences systematically summarized the latest progress in the research field of spinal cord injury regeneration and repair, looks forward to the challenges and future development trends in this research field, and provides important guidance for spinal ...

    14 Jan 2022
  • A Dual-functional Immunoregulatory Hydrogel Promotes Neural Regeneration after Spinal Cord Injury
    A Dual-functional Immunoregulatory Hydrogel Promotes Neural Regeneration after Spinal Cord Injury

    Research group led by Prof. DAI Jianwu from the Chinese Academy of Sciences developed a multifunctional scaffold by modifying a photocrosslinking gelatin hydrogel with a cationic polymer, polyamidoamine, and an anti-inflammatory cytokine, interleukin-10 (IL-10), to effectively regulate the immune microenvironment after spinal cord injury, reduc...

    13 Jan 2022
  • Researchers Reveal Mechanism of Lipid Storage and Mitochondrial Metabolism Regulated by NAD Kinase NADK
    Researchers Reveal Mechanism of Lipid Storage and Mitochondrial Metabolism Regulated by NAD Kinase NADK

    A research team led by Prof. HUANG Xun from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences revealed that NAD kinase (NADK) , which phosphorylates NAD+ to produce NADP+, regulates lipid storage and mitochondrial metabolism in fat tissue through supporting de novo lipogenesis.

    30 Dec 2021
  • Chloroplast Co-chaperonin Links Protein Folding and Degradation
    Chloroplast Co-chaperonin Links Protein Folding and Degradation

    Researchers from Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, discovered a novel function of the Cpn60 co-chaperonin in addition to its known function in promoting folding: slowing down the degradation activity of chloroplast ClpP by capping the substrate entrance.

    30 Nov 2021