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Research News
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A Rare Gain of Function Mutation in a Wheat Tandem Kinase Confers Resistance to Powdery Mildew
Recently, a team led by Prof. LIU Zhiyong at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, in collaboration with the team led by Prof. LI Hongjie at the Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, identified a rare gain of function mutation in a wheat tandem kinase that confers resist...
02 Feb 2020
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Directed Evolution of Endogenous Genes by Dual Cytosine and Adenine Base Editors to Accelerate Agronomic Trait Development
Researchers from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, engineered five saturated targeted endogenous mutagenesis editors (STEMEs) and generated de novo mutations to facilitate directed evolution of plant genes, which can be used to accelerate agronomic trait development.
10 Jan 2020
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MED25 Regulates the Alternative Splicing of JAZ Genes through Recruitment of Splicing Factors PRP39 and PRP40
A team led by Prof. LI Chuanyou at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, revealed a mechanistic function of the Mediator subunit MED25 in coupling the alternative splicing of JAZ genes with fine tuning of jasmonate signaling.
19 Dec 2019
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The Widespread Dosage Imbalance during S Phase Shapes the DNA Replication Program
Researchers from QIAN Wenfeng Lab at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences observed widespread dosage imbalance between early- and late-replicating genes using single-cell RNA-seq and the genes encoding members of a protein complex replicate simultaneously so that the dosage balance among subunits of th...
06 Dec 2019
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Researchers Developed a New Non-human Primate Model Induced by Environmental Factors for Autism
An international research team established a novel drug-induced animal model of autism by revealing the effects of valproic acid (VPA) on neural development and behavior in the offspring of non-human primates.
06 Nov 2019
