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Research News
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Canonical Wnt Efficiently Induces Trophoblastic Syncytiotrophoblast Layer II Cells Differentiation
ZHANG Jian’s group from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, found efficient induction of Syncytiotrophoblast Layer II cells from trophoblast stem cells by canonical Wnt signaling Activation.
24 Nov 2017
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Scientists Uncovered a Novel Presynaptic Function of the Autism Associated Gene SHANK
The research group led by Prof. ZHANG Yongqing at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, in collaboration with other groups at home and abroad uncovered a novel presynaptic function of the autism associated gene SHANK and offers novel insights into synaptic protein functions and the neuronal mechanisms ...
17 Nov 2017
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cTAGE5 Interacts with Sec22b to Regulate Proinsulin Trafficking
Researchers in XU Zhiheng’s group from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences found that cTAGE5 interacts and is likely to coordinate with Sec22b to play an essential role in proinsulin trafficking from ER-to-Golgi.
15 Nov 2017
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Dpb3-Dpb4 Complex Coordinately Regulates the Heterochromatin Inheritance
Dr. CHEN Yuhang’s group from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, collaborated with LI Fei’s group in New York University, revealed the coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex.
08 Nov 2017
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Histone H3 Phosphorylation Requires Cohesion and Centromere Activity in Maize
Dr. HAN Fangpu’s lab in the Institute of Genetics and Developmental Biology (IGDB), Chinese Academy of Sciences, found cohesion and centromere activity are required for histone H3 phosphorylation in maize.
02 Nov 2017
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Chloroquine Prevents ZIKV Infection and Its Associated Congenital Microcephaly in Mice
Researchers in XU Zhiheng’s group from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, found that Chloroquine could inhibit ZIKV-associated morbidity and mortality in mice, and prevent ZIKV ZIKV-caused congenital microcephaly in mouse model.
02 Nov 2017
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Chinese Scientists Uncover the Critical Neurovirulence Determinant of Zika Virus Contributing to Fetal Microcephaly
Researchers in QIN Chengfeng Qin’s group from Academy of Military Medical Sciences and XU Zhiheng’s group from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, found that a single serine to asparagine substitution (S139N) in the viral polyprotein substantially increased the neurovirulence of Zika virus, leading...
02 Nov 2017
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Cross-talk between MT +TIPs and -TIPs Regulates Intracellular Transport
Researchers from MENG Wenxiang group at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, discovered the relationship between CAMSAPs and end-binding protein and revealed they could regulats Intracellular Transport
20 Oct 2017
