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Research News
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IGDB Scientists Revealed a Novel Regulation Mechanism of ABA Co-receptor ABI1 by the E2-E3 Complex UBC27-AIRP3
The team led by Prof. XIE Qi from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences uncovered a novel E2-E3 complex in ABI1 degradation, as well as important and complex regulation of ABA signaling by the ubiquitination system.
20 Oct 2020
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IGDB Scientists Identify a Molecular Connection between Biomass Production and Nitrogen Utilization Efficiency in Rice
The group of Prof. ZHOU Yihua from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, recently reported the identification of a variation at the MYB61, a transcription factor that is controlled by a nitrogen integrative regulator GRF4, which explains the differences in nitrogen utilization efficiency and cellulose ...
20 Oct 2020
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IGDB Scientists Revealed the Mechanism of ESCRT-I Component VPS23A Degradation in ABA Signaling
a research team led by Prof. XIE Qi from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, revealed how the ESCRT-I component VPS23A was controlled by upstream factors to finely modulate the protein level of ABA receptors in ABA signaling.
18 Sep 2020
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Unbalanced Microtubule Networks Launch Establishment of Neuronal Polarity
Prof. MENG Wenxiang’s group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences recently reported a new mechanism by which microtubule networks instruct neuronal polarity.
25 Aug 2020
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Researchers Reveal Mitochondrial Metabolite Mediates Longevity through Epigenomes
A research team led by Dr. TIAN Ye from the Institute of Genetics and Developmental Biology, the Chinese Academy of Sciences found that mitochondrial perturbations alter the nuclear epigenome that determines the organismal lifespan, a process mediated by the nucleosome remodeling and histone deacetylase (NuRD) complex in response to acetyl-CoA l...
01 Aug 2020
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Researchers Develop New Cytosine Base Editors with High Specificity and Precision
Researchers from the Chinese Academy of Sciences created two new cytosine base editors (CBEs) based on a truncated human APOBEC3 cytidine deaminase (A3Bctd) and developed a high-throughput assay for assessing sgRNA-independent deamination changes in plant CBEs.
28 Jul 2020
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Researchers Consruct a Dynamic Transcriptional and Chromatin Accessibility Landscape of Medaka Embryogenesis
A joint team reported a multi-omics landscape of medaka embryogenesis profiled by long-read RNA-seq, short-read RNA-seq, and ATAC-seq, and provided the first comprehensive omics datasets of medaka embryogenesis.
03 Jul 2020
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Scientists Develop Novel Predictable Multi-nucleotide Deletion Systems in Plants
The research team led by Prof. GAO Caixia of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences developed a series of APOBEC-Cas9 fusion-induced deletion systems (AFIDs) that combine Cas9 with human APOBEC3A (A3A), uracil DNA-glucosidase (UDG) and AP lyase and successfully induced novel precise, predictable mu...
30 Jun 2020
