• Crmp2 Plays a Critical Role in the Brain Circuitry Formation and Maintenance
    Crmp2 Plays a Critical Role in the Brain Circuitry Formation and Maintenance

    Scientists from XU Zhiheng’s group at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and MING Guoli’s group at Johns Hopkins University School of Medicine revealed that Crmp2, a schizophrenia risk gene, plays a critical role in neural development, circuit integrity and brain function.

    30 Jun 2016
  • A New Factor Involved in Lipid Transport and Related to Fatty Liver Disease
    A New Factor Involved in Lipid Transport and Related to Fatty Liver Disease

    Scientists from XU Zhiheng’s group at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, found that meningioma-expressed antigen 6 (Mea6) plays a critical role in lipid transportation in mice liver.

    24 Jun 2016
  • IGDB Scientists Revealed the Conserved Novel Mechanism of ERAD Tuning between Plant and Mammals
    IGDB Scientists Revealed the Conserved Novel Mechanism of ERAD Tuning between Plant and Mammals

    Researchers from Dr. XIE Qi’s group at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, elucidated the key molecular mechanism of ERAD tuning in plant and found he regulation of UBC32 (or UBE2J1) by HRD1 complex is conserved between plants and mammals .

    22 Jun 2016
  • A Multiprotein Complex Involves in Regulation of Cortical Neuronal Migration
    A Multiprotein Complex Involves in Regulation of Cortical Neuronal Migration

    Researchers in XU Zhiheng’s group from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, found that TGF-β-activated kinase 1 (TAK1) played an important role in TGF-β signaling controlled neuronal migration through regulation of c-Jun N-terminal kinase (JNK) activity.

    15 Jun 2016
  • IGDB Scientists Revealed New Mechanism of Autism Pathogenesis
    IGDB Scientists Revealed New Mechanism of Autism Pathogenesis

    The research group led by Dr. ZHANG Yongqing at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, found that Drosophila mutants of ube3a had excess synaptic boutons and endocytic defects at the neuromuscular junctions, which suggests a previously unknown molecular mechanism of autism pathogenesis.

    15 Jun 2016
  • miR172a, a New Gene Improves Salt Tolerance in Soybean
    miR172a, a New Gene Improves Salt Tolerance in Soybean

    The groups of Prof. ZHANG Jinsong and Prof. CHEN Shouyi from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, found that soybean miR172a improves salt tolerance and can function as a long distance signal.

    02 Jun 2016
  • A Multiallelic Gene MS5 Regulates Male Fertility in Brassica napus
    A Multiallelic Gene MS5 Regulates Male Fertility in Brassica napus

    The researchers from CHENG Zhukuan’s lab at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, collaborated with YANG Guangsheng’s lab at Huazhong Agricultural University, found that MS5 participates in the progression of meiosis during early prophase I and regulates gametogenesis in Brassica napus.

    02 Jun 2016
  • IGDB Scientists Revealed New Mechanism of Histone Demethylase Genome-wide Targeting
    IGDB Scientists Revealed New Mechanism of Histone Demethylase Genome-wide Targeting

    The research group led by Dr. CAO Xiaofeng at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, found a novel targeting mechanism of an H3K27me3 demethylase that regulates plant development, including organ boundary formation.

    20 May 2016